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SMMHC Mouse anti-Human, Mouse, Porcine, Rat, Clone: 5C6D3, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 60222-1-IG-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16887235

  • 121.38€ / 20 microlitros
Fecha estimada de envío: 26-05-2022
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Descripción

Descripción

The protein encoded by MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of MYH11, and its 3′ end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Especificaciones

Especificaciones

SMMHC
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O08638, P35749, P81271, Q63862
Myh11
SMMHC Fusion Protein Ag13397
20 μL
Primary
Mouse, Rat, Human, Porcine
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
5C6D3
Unconjugated
MYH11
MYH11, Myosin 11, Myosin heavy chain 11, SMHC, SMMHC, SMM-HC, smooth muscle myosin heavy chain
Mouse
Protein G
RUO
100627924, 17880, 24582, 4629
Antibody
IgG1
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales