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ACROBiosystems Rhesus macaque GITR / TNFRSF18 Protein, Fc Tag

Marca:  ACROBiosystems GIR-C5255-100UG

Detalles adicionales : Peso : 0.00001kg

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Código de producto. 15896837

  • 419.88€ / 100 microgramos
Fecha estimada de envío: 11-04-2024
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Descripción

Descripción

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.3 kDa. As a result of glycosylation, the protein migrates as 48 kDa under reducing (R) condition, and 85 kDa under non-reducing (NR) condition (SDS-PAGE).
Especificaciones

Especificaciones

41.3 kDa
Rhesus macaque GITR, Fc Tag (GIR-C5255) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # F7DDV8).
-20°C
GITR
Rhesus Macaque
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
100 μg
Gln 26 - Glu 161
AITR,GITR,TNFRSF18,CD357
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
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