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ACROBiosystems Rhesus macaque GITR / TNFRSF18 Protein, Fc Tag
Marca: ACROBiosystems GIR-C5255-100UG
Detalles adicionales : Peso : 0.00001kg
Descripción
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.3 kDa. As a result of glycosylation, the protein migrates as 48 kDa under reducing (R) condition, and 85 kDa under non-reducing (NR) condition (SDS-PAGE).Especificaciones
| Powder | |
| >95% as determined by SDS-PAGE | |
| Rhesus macaque GITR, Fc Tag (GIR-C5255) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # F7DDV8). | |
| -20°C | |
| GITR | |
| Fc Tag | |
| Less than 1.0 EU / µg by the LAL method. | |
| Immune Checkpoint Proteins |
| 41.3 kDa | |
| 100 µg | |
| Gln 26 - Glu 161 | |
| AITR,GITR,TNFRSF18,CD357 | |
| Unconjugated | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Rhesus macaque |