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ACROBiosystems Rhesus macaque CD4 Protein, His Tag
Marca: ACROBiosystems CD4-C52H7-100UG
Detalles adicionales : Peso : 0.00001kg
Descripción
T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.3 kDa. The protein migrates as 50-57 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
| 42.3 kDa | |
| Rhesus macaque CD4, His Tag (CD4-C52H7) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8). | |
| -20°C | |
| CD4 | |
| Rhesus Macaque | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 100 μg | |
| Lys 26 - Trp 390 | |
| CD4,CD4mut,LEU3 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |