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Phospho-INSR (Thr1160) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA595679
Detalles adicionales : Peso : 0.01000kg
Descripción
Antigen Affinity Purified from Pooled Serum
INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.Especificaciones
| Phospho-INSR (Thr1160) | |
| Polyclonal | |
| Unconjugated | |
| INSR | |
| INSR | |
| Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr1160 conjugated to KLH | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| 0.25 mg/mL | |
| 10mM HEPES with 100μg/ml BSA, 50% glycerol and no preservative; pH 7.5 | |
| P06213 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3643 | |
| -20°C | |
| Liquid |