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P-selectin Mouse anti-Human, Clone: 3G2C7, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 60322-1-IG-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16887415

  • 121.38€ / 20 microlitros
Fecha estimada de envío: 01-07-2022
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Descripción

Descripción

P-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes (white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.
Especificaciones

Especificaciones

P-selectin
Monoclonal
1.08 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P16109
SELP
P-selectin Fusion Protein Ag4124
20 μL
Primary
Human
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
3G2C7
Unconjugated
SELP
CD62, CD62P, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, P-selectin, SELP
Mouse
Protein A
RUO
6403
Antibody
IgG2b
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales