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NK1.1 (CD161) Mouse, anti-Mouse, PE, Clone: PK136, STEMCELL Technologies

Mouse Monoclonal Antibody

Encompass_Preferred

en la oferta

Especificaciones

Antígeno NK1.1 (CD161)
Clon PK136
Aplicaciones CyTOF, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
Clasificación Monoclonal
Conjugado PE
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Productos 2
Código de producto Marca Cantidad Price Quantity & Availability  
Product Code Brand Cantidad Price Quantity & Availability  
17177621
Encompass_Preferred
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Stemcell Technologies
100-0460 		25 μg
en la oferta
25 microgramos
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17187621
Encompass_Preferred
missing translation for 'viewDocuments'
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Stemcell Technologies
100-0461 		100 μg
en la oferta
100 microgramos
View alternative products
missing translation for 'toSaveUpto'  » 		N/A
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Este artículo requiere una actualización de precios antes de ser solicitado.

Solicite el precio de este artículo aquí.

Description

Description

  • The PK136 antibody reacts with murine NK1.1 (CD161), an ∼80 kDa homodimeric type 2 transmembrane glycoprotein and C-type lectin receptor expressed on NK cells, NK-T cells, and rare subsets of T cells and monocytes in select strains of mice
  • NK1.1 is encoded by the Klrb1b and Klrb1c genes, which specify CD161b and CD161c polypeptides, respectively
  • CD161b is expressed only by Swiss NIH and SJL mice, and CD161c by certain strains such as C57BL, FVB/N, and NZB (but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, NOD, SJL, or 129)
  • NK1.1 has functional roles in modulating several processes, including the activation and proliferation of NK cells, induction of interferon-γ production, and release of cytotoxic granules
  • Its expression on the cell surface is specifically upregulated by IL-12
  • For detection of NK cells in NK1.1- strains, Anti-Mouse CD49b Antibody, Clone DX5 (Catalog #60020) is recommended
  • DX5 recognizes CD49b (integrin α2), another commonly used NK cell marker
Specifications

Specifications

NK1.1 (CD161)
CyTOF, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
PE
Mouse
PK136
Monoclonal
Mouse
Primary
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