MRPS25 Polyclonal Antibody, Invitrogen™

Descripción

Immunogen sequence: LREEEEEKKQ LSHPANFGPR KYCLRECICE VEGQVPCPSL VPLPKEMRGK YKAALKADAQ D Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4.