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Invitrogen™ Human MAP4K1 (HPK1), GST Tag Recombinant Protein
Human MAP4K1 (HPK1), GST Tag Recombinant Protein
Marca: Invitrogen™ PV6356
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Descripción
MAP4K1 (also known as HPK1) or Hematopoietic progenitor kinase 1 is a hematopoietic cell-restricted member of the Ste20 serine/threonine kinase super family. MAP4K1 is a tissue-specific upstream activator of the MEKK/JNK/SAPK signaling pathway. MAP4K1 diminishes T cell receptor (TCR) signaling activity and T cell proliferation by phosphorylating the adaptor protein SLP-76. Recombinant human MAP4K1 (1-346) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Related Product:
LanthaScreen™ Eu Kinase Binding Assay
Especificaciones
| Kinase Assay | |
| 100 μg | |
| aa 1-346 | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. |
|
| Baculovirus | |
| Recombinant, Full Length |
| 65.0 kDa | |
| MAP4K1 | |
| Human | |
| GST tag | |
| Serine/Threonine Kinase | |
| Kinases & Inhibitors | |
| Liquid |