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K-cadherin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA529984
Detalles adicionales : Peso : 0.01000kg
Descripción
Recommended positive controls: H1299, HCT116. Predicted reactivity: Mouse (97%), Rat (98%), Chicken (85%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.Especificaciones
| K-cadherin | |
| Polyclonal | |
| Unconjugated | |
| CDH6 | |
| CAD6; CADH6; cadherin 6; cadherin 6, type 2, K-cadherin; cadherin 6, type 2, K-cadherin (fetal kidney); Cadherin6; cadherin-6; Cdh6; k cadherin; KCAD; K-cadherin; Kidney cadherin | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1004 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 20% glycerol and 0.01% thimerosal; pH 7 | |
| P55285 | |
| CDH6 | |
| Recombinant fragment corresponding to a region within amino acids 325 and 606 of Human K cadherin | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |