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IREB2 Polyclonal Antibody, Invitrogen™
Goat Polyclonal Antibody
Marca: Invitrogen PA519158
Detalles adicionales : Peso : 0.01000kg
Descripción
This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).Especificaciones
| IREB2 | |
| Polyclonal | |
| Unconjugated | |
| IREB2 | |
| ACO3; D9Ertd85e; FLJ23381; im:7153062; Ireb2; IRE-BP 2; IREBP2; Iron regulatory protein 2; iron responsive element binding protein 2; iron-regulatory protein 2; iron-responsive element binding protein 2; iron-responsive element-binding protein 2; Iron-responsive element-binding protein 2-like protein; IRP2; IRP2AD | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 3658, 64602, 64831 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P48200, Q62751, Q811J3 | |
| IREB2 | |
| Synthetic peptide sequence (SIHYEGSEYKLSHGS) corresponding to the internal amino acids of IREB2 | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |