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STEMCELL Technologies Human Recombinant FGF-7 (KGF)
Fibroblast growth factor 7
Marca: STEMCELL Technologies 78046.2
Detalles adicionales : Peso : 0.00001kg
Descripción
- Fibroblast growth factor 7 (FGF-7) is a member of the FGF family, and acts exclusively through a subset of FGF receptor isoforms expressed predominantly by epithelial cells (Finch & Rubin)
- FGF-7 seems to act specifically on epithelial cells and stimulates proliferation, migration, and differentiation of these cells, and also participates in epithelial protection and repair both in vitro and in vivo (Finch & Rubin; Werner)
- In contrast, FGF-7 is produced solely by cells of mesenchymal origin, and functions as a paracrine mediator of mesenchymal-epithelial communication (Rubin et al.) FGF-7 has also been shown to supplement several wound-healing properties of bioengineered skin (Erdag et al.) and to induce autophagy in human keratinocytes (Belleudi et al.) Additionally, FGF-7 has a role in pluripotent stem cell differentiation to endodermal pancreatic-like insulin-producing cells and thymic epithelial cells (Inami et al.; Niu et al.)
Especificaciones
| Fibroblast growth factor-7, HBGF-7, Heparin-binding growth factor 7, Keratinocyte growth factor | |
| 1000 μg | |
| Endoderm, PSC-Derived; Hematopoietic Stem and Progenitor Cells; Keratinocytes; Mammary Cells; Mesenchymal Stem and Progenitor Cells; Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Pluripotent Stem Cells; Prostate Cells | |
| ≥95% |