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ACROBiosystems Human PD-L2 / B7-DC Protein, mouse IgG1 Fc Tag

Marca:  ACROBiosystems PD2-H52A5-100UG

Detalles adicionales : Peso : 0.00001kg

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Código de producto. 15877507

  • 350.80€ / 100 microgramos
Fecha estimada de envío: 24-04-2024
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Descripción

Descripción

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

This protein carries a mouse IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.9 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

AAI13679
100 μg
Leu 20 - Pro 219
PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2
Unconjugated
Mouse IgG Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by reduced SDS-PAGE
48.9 kDa
Human PD-L2, Mouse IgG1 Fc Tag (PD2-H52A5) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 219 (Accession # AAI13679).
-20°C
PD-L2
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
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