Invitrogen™ Human Coagulation Factor XI ELISA Kit
Human Coagulation Factor XI quantitates human Coagulation Factor XI in serum, plasma, supernatant.
Marca: Invitrogen™ EH118RBX10
Detalles adicionales : Peso : 2.50000kg
Human Coagulation Factor XI quantitates human Coagulation Factor XI in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Coagulation Factor XI.This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
|1600027G01Rik; AI503996; Cf11; Coagulation factor XI; Coagulation factor XIa heavy chain; Coagulation factor XIa light chain; F11; FXI; LRRGT00086; Plasma thromboplastin antecedent; PTA|
|Colorimetric Microplate Reader|
|Research Use Only|
|2°C to 8°C|
|1 hr 20 min|
|10 to 2,500 pg/mL|
|Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers|
|10 x 96 Tests|
|Plasma, 50 μL; Serum, 50 μL; Supernatant, 50 μL|
|4 hr 45 min|