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ACROBiosystems Human CD27 Ligand / CD70 Protein, Mouse IgG2a Fc Tag, low endotoxin

low endotoxin

423.38€ - 2818.49€

Especificaciones

Número de acceso NP_001243.1
Peso molecular 44.0 kDa
Fuente Human CD27 Ligand, Mouse IgG2a Fc Tag, low endotoxin (CDL-H525a) is expressed from human 293 cells (HEK293). It contains AA Gln 39 - Pro 193 (Accession # P32970-1).
Inmunógeno Gln 39 - Pro 193
Requisitos de almacenamiento -20°C
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15886417
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ACROBiosystems
CDL-H525A-100UG
100 μg
423.38€
100 microgramos
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Fecha estimada de envío: 21-06-2024
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15896417
Ver documentos Detalles de la promoción
ACROBiosystems
CDL-H525A-1MG
1 mg
2818.49€
1 miligramo
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»
Fecha estimada de envío: 21-06-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.

This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 44.0 kDa. The protein migrates as 50-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_001243.1
Human CD27 Ligand, Mouse IgG2a Fc Tag, low endotoxin (CDL-H525a) is expressed from human 293 cells (HEK293). It contains AA Gln 39 - Pro 193 (Accession # P32970-1).
-20°C
CD27 Ligand
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
44.0 kDa
Gln 39 - Pro 193
CD70,CD27LG,TNFSF7,TNFSF7G,CD27L
Unconjugated
Mouse IgG Fc Tag
Less than 0.1 EU / μg by the LAL method.
Powder
>85% as determined by SDS-PAGE
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