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HK2 Monoclonal Antibody (3D3), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA515679
Detalles adicionales : Peso : 0.01000kg
Descripción
MA5-15679 targets HK2 in indirect ELISA, FACS, IHC and WB applications and shows reactivity with Human samples. The MA5-15679 immunogen is purified recombinant fragment of human HK2 expressed in E. Coli. MA5-15679 detects HK2 which has a predicted molecular weight of approximately 102kDa.
In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.Especificaciones
HK2 | |
Monoclonal | |
Conc. Not Determined | |
ascites with 0.03% sodium azide | |
P52789 | |
Hk2 | |
Purified recombinant fragment of human HK2 expressed in E. Coli. | |
RUO | |
3099 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
3D3 | |
Unconjugated | |
Hk2 | |
AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738 | |
Mouse | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |