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GTPBP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 11557-1-AP-150UL
Detalles adicionales : Peso : 0.00010kg
Descripción
Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP2 (GTP-binding protein 2) is a 602 amino acid G protein that is expressed in kidney, skeletal muscle, testis, brain and thymus, though it is not detected in liver. Expression of GTPBP2 is enhanced by ©-interferon stimulation in HeLa cells, THP-1 cells and thioglycollate-elicited mouse peritoneal macrophages. There are four isoforms of GTPBP2 that are expressed as a result of alternative splicing events. Since mutation of the gene encoding GTPBP1 does not lead to any phenotypic abnormalities, it is thought that there may be a genetic redundancy to make up for GTPBP1 lack-of-function. GTPBP2 shares 44% sequence similarity with GTPBP1 and also overlaps in expression pattern, suggesting that the GTPBP2 gene may compensate for GTPBP1 genetic abnormalities.Especificaciones
GTPBP2 | |
Polyclonal | |
Unconjugated | |
GTPBP2 | |
GTP binding protein 2, GTPBP2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
363195, 54676, 56055 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.17 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q3UJK4, Q9BX10 | |
Gtpbp2 | |
GTPBP2 Fusion Protein Ag2113 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |