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Cytokeratin 19 Mouse anti-Human, Clone: 3G1E4, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 60187-1-IG-150UL
Detalles adicionales : Peso : 0.00010kg
Descripción
This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
Cytokeratin 19 is part of a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40-68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial maligcies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. For example, cytokeratin 19 is not expressed in hepatocytes, therefore, it is useful in the identification of liver metastasis.Especificaciones
Cytokeratin 19 | |
Monoclonal | |
1.13 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P08727 | |
KRT19 | |
Cytokeratin 19 Fusion Protein Ag7407 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG2b |
Immunohistochemistry (Paraffin), Western Blot | |
3G1E4 | |
Unconjugated | |
KRT19 | |
CK 19, CK19, Cytokeratin 19, K19, K1CS, keratin 19, KRT19 | |
Mouse | |
Protein A | |
RUO | |
3880 | |
-20°C | |
Liquid |