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COMT 293T Cell Overexpression Lysate (Denatured), Abnova
Marca: Abnova H00001312-T01.100uL
Detalles adicionales : Peso : 0.00010kg
Descripción
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
- Transfected Cell Line: 293T
- Plasmid: pCMV-COMT full-length
- Host: Human
- Molecualr Weight: 24.4kDa
- Storage Buffer: 1X Sample Buffer (50mM Tris-HCl, 2% SDS, 10% glycerol, 300mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Western Blotting
Especificaciones
| Western Blot | |
| COMT 293T Cell Transient Overexpression Lysate(Denatured) | |
| 24.4 | |
| pCMV-COMT full-length | |
| 100 μL | |
| Human |
| 293T | |
| NM_007310.1 | |
| 6.8 | |
| Transient overexpression cell Lysate was tested with Anti-COMT antibody (H00001312-B01) by western blotting | |
| 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) | |
| Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Seguridad y manipulación
Nombre del producto
Palabra de advertencia
Clasificación
Indicaciones de peligro
Consejos de prudencia
Otros peligros
- 100UL COMT 293T Cell Transient Overexpression Lysa
Palabra de advertencia
- Atención
Clasificación
- Sensibilización cutánea Categoría 1
Indicaciones de peligro
- H317-Puede provocar una reacción alérgica en la piel.
Consejos de prudencia
- P261-Evitar respirar el polvo/el humo/el gas/la niebla/los vapores/el aerosol.
- P272-Las prendas de trabajo contaminadas no podrán sacarse del lugar de trabajo.
- P280-Llevar guantes/prendas/gafas/máscara de protección.
Otros peligros
- MIXTURE LIST-Contém: Mercaptoethanol