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Complement factor B Mouse anti-Human, Clone: 8D2B6, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66154-1-IG-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16817775

  • 109.00€ / 20 microlitros

Envío estimado: 22-10-2021

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Descripción

Descripción

This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5′ end of the gene for complement component 2.
Especificaciones

Especificaciones

Complement factor B
8D2B6
Unconjugated
CFB
Liquid
CFB
Complement factor B Fusion Protein Ag19107
Antigen Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Western Blot, Immunohistochemistry (Paraffin)
0.6 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P00751
BF, BFD, C3/C5 convertase, CFAB, CFB, Complement factor B, FB, FBI12, GBG, Glycine rich beta glycoprotein, H2 Bf, PBF2, Properdin factor B
Mouse
IgM
20 μL
-20°C
Primary
629
Videos
SDS
Documentos
Certificados