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CD61 Monoclonal Antibody (HM beta 3.1), PE, Invitrogen™
Armenian Hamster Monoclonal Antibody
Marca: Invitrogen MA516709
Detalles adicionales : Peso : 0.01000kg
Descripción
Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4oC in the dark. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectrin. CD61 is a 105 kDa glycoprotein that associates with either the alpha 11b integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, Von Willebrand Factor, vitronectin and thrombospondin. The CD61 protein product is composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. CD61 is found along with the alpha IIb chain in platelets. Like other integrins, CD61 is known to participate in cell adhesion as well as cell-surface mediated signaling. Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.Especificaciones
CD61 | |
Monoclonal | |
Conc. Not Determined | |
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide | |
O54890 | |
ITGB3 | |
Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4 | |
100 Tests | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
Flow Cytometry | |
HM beta 3.1 | |
PE | |
ITGB3 | |
antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa | |
Armenian Hamster | |
Protein G | |
RUO | |
16416, 29302 | |
4° C, store in dark, DO NOT FREEZE! | |
Lyophilized |