CD56/NCAM-1 Ab-4 Mouse Monoclonal Antibody, Epredia™

Description

Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule which is glycosylated or sialylated to produce the mature species. NCAM (CD56) is reported to express on most neuroectodermal derived cell lines, tissues, and neoplasms such as retinoblastoma, medullblastoma, astrocytoma, and neuroblastoma. It is also expressed on some mesodermally derived tumors such as rhabdomyosarcoma and also on natural killer cells.

Host Species: Mouse

Clone: 56C04; same as 123A8

Isotype: IgG1/κ

Species Reactivity: Human. Others not known

Epitope: Not determined

Immunogen: Membrane preparation of a small cell lung carcinoma

Molecular Weight: 180, 145 and 125 kDa

Positive Control: Neuroblastoma

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)