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CD45 Rat, anti-Mouse, Biotin, Clone: 30-F11, STEMCELL Technologies

Rat Monoclonal Antibody

Marca:  Stemcell Technologies 60030BT.1

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17188621

  • 91.77€ / 50 microgramos
Fecha estimada de envío: 18-11-2022
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Descripción

Descripción

  • The 30-F11 antibody reacts with an extracellular epitope found on all isoforms and both alloantigens (CD45.1 and CD45.2) of mouse CD45, a type I transmembrane glycoprotein expressed on the surface of most hematopoietic cells except mature erythrocytes, platelets and plasma cells; expression of CD45 is lost during differentiation of these cell types
  • CD45 is a member of the protein tyrosine phosphatase family and functions in a number of immunoregulatory processes, including cell activation, growth, differentiation and oncogenic transformation
  • The large cytoplasmic portion of CD45 contains two tyrosine phosphatase domains, one which is enzymatically active, that are involved in modulating the function of intracellular substrates such as the Src kinases Lck and Fyn
  • Several isoforms of CD45 have been identified, the expression of which differs according to cell type and functional status
Especificaciones

Especificaciones

CD45
Monoclonal
Biotin
50 μg
Mouse
Granulocytes and Subsets, Hematopoietic Stem and Progenitor Cells, Lymphocytes, Myeloid Cells
Immunofluorescence, Immunocytochemistry, Flow Cytometry, Western Blot, Immunohistochemistry
30-F11
Rat
Primary
IgG2b κ
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales