missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD223 (LAG-3) Monoclonal Antibody (3DS223H), NovaFluor™ Blue 510, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen H048T02B01
Detalles adicionales : Peso : 0.02000kg
Descripción
This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells). This 3DS223H antibody will recognize a formaldehyde-fixed epitope. Applications Reported: This 3DS223H antibody has been reported for use in flow cytometric analysis. Applications Tested: This 3DS223H antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5μL (0.06μg) per test NovaFluor dyes are not compatible with DNA intercalating viability dyes. Do not use viability dyes such as propidium iodide, 7-actinomycin D (7-AAD) and DAPI. Invitrogen LIVE/DEAD Fixable Dead Cell stains are recommended for use with NovaFluor dyes. Each NovaFluor conjugate or kit is shipped with CellBlox Blocking Buffer. Excitation: 496 nm; Emission: 511 nm; Laser: 488 nm (Blue) Laser
CD223 (LAG-3) Monoclonal antibody specifically detects CD223 (LAG-3) in Human samples. It is validated for Flow Cytometry.Especificaciones
| CD223 (LAG-3) | |
| Monoclonal | |
| 1 μg/Test | |
| PBS with 0.09% sodium azide; pH 7.2 | |
| P18627 | |
| LAG3 | |
| Affinity chromatography | |
| RUO | |
| 3902 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
| Flow Cytometry | |
| 3DS223H | |
| NovaFluor Blue 510 | |
| LAG3 | |
| Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3 | |
| Mouse | |
| 25 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |