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CD150 (SLAM) Hamster, anti-Mouse, PE, Clone: TC15-12F12.2, STEMCELL Technologies
Hamster Monoclonal Antibody
Marca: Stemcell Technologies 60036PE
Detalles adicionales : Peso : 0.00110kg
Descripción
- The TC15-12F12
- 2 antibody reacts with CD150 (signaling lymphocyte activation molecule or SLAM), an ∼75 kDa type I transmembrane glycoprotein that plays multiple roles in the immune response by serving as a cell adhesion molecule and/or coreceptor
- It is differentially expressed by T cells, immature thymocytes, B cells, dendritic cells, macrophages, and endothelial cells
- The expression pattern differs according to cell type and activation status
- Expression is rapidly induced upon activation of T cells, B cells and dendritic cells, with synthesis by T cells being maintained on Th1 but not Th2 clones
- CD150-mediated co-stimulation of TCR-activated T cells enhances the production of IFN-γ by Th1 cells, a response that can be augmented by binding of the TC15-12F12
- 2 antibody
- CD150 is thought to mediate signal transduction by associating with the intracellular protein tyrosine phosphatase, SHP-2
Especificaciones
| CD150 (SLAM) | |
| Monoclonal | |
| PE | |
| 100 μg | |
| Mouse | |
| Hematopoietic Stem and Progenitor Cells |
| Immunohistochemistry, Flow Cytometry, Immunofluorescence, Functional Assay, Immunoprecipitation | |
| TC15-12F12.2 | |
| Hamster | |
| Primary | |
| IgG2a λ |