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CD150 (SLAM) Hamster, anti-Mouse, PE, Clone: TC15-12F12.2, STEMCELL Technologies

Hamster Monoclonal Antibody

Marca:  Stemcell Technologies 60036PE

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17198681

  • 456.19€ / 100 microgramos
Fecha estimada de envío: 14-11-2022
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Descripción

Descripción

  • The TC15-12F12
  • 2 antibody reacts with CD150 (signaling lymphocyte activation molecule or SLAM), an ∼75 kDa type I transmembrane glycoprotein that plays multiple roles in the immune response by serving as a cell adhesion molecule and/or coreceptor
  • It is differentially expressed by T cells, immature thymocytes, B cells, dendritic cells, macrophages, and endothelial cells
  • The expression pattern differs according to cell type and activation status
  • Expression is rapidly induced upon activation of T cells, B cells and dendritic cells, with synthesis by T cells being maintained on Th1 but not Th2 clones
  • CD150-mediated co-stimulation of TCR-activated T cells enhances the production of IFN-γ by Th1 cells, a response that can be augmented by binding of the TC15-12F12
  • 2 antibody
  • CD150 is thought to mediate signal transduction by associating with the intracellular protein tyrosine phosphatase, SHP-2
Especificaciones

Especificaciones

CD150 (SLAM)
Monoclonal
PE
100 μg
Mouse
Hematopoietic Stem and Progenitor Cells
Immunoprecipitation, Functional Assay, Immunofluorescence, Flow Cytometry, Immunohistochemistry
TC15-12F12.2
Hamster
Primary
IgG2a λ
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales