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BAX Mouse anti-Human, Mouse, Rat, Clone: 4G5E8, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 60267-1-IG-150UL
Detalles adicionales : Peso : 0.00010kg
Descripción
BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3′ UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa).BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis. Overexpression of BAX functions to promote cell death. BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.Especificaciones
BAX | |
Monoclonal | |
1.6 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q07812, Q07813, Q63690 | |
Bax | |
BAX Fusion Protein Ag21068 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG2b |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
4G5E8 | |
Unconjugated | |
BAX | |
Apoptosis regulator BAX, BAX | |
Mouse | |
Protein A | |
RUO | |
12028, 24887, 581 | |
-20°C | |
Liquid |