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PKN2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA534784

Detalles adicionales : Peso : 0.01000kg

Código de producto. 15388681

  • 338.00€ / 100 microlitros


Fecha de envío estimada
del proveedor 31-10-2019
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Descripción

Descripción

PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluro-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF). Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.
Especificaciones

Especificaciones

PKN2
Polyclonal
Unconjugated
PKN2
Liquid
PKN2
Recombit fragment contains a sequence corresponding to a region within amino acids 487 and 984 of PKN2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Q16513
PAK2, PRK2, PRKCL2, PRO2042, Pak-2, PKN gamma, cardiolipin-activated protein kinase Pak2, protein kinase C-like 2, protein-kinase C-related kinase 2, serine/threonine-protein kinase N2
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5586
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