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PI3K p85 alpha Mouse anti-Human, Mouse, Non-human primate, Rat, Clone: U13, Invitrogen™

Mouse Monoclonal Antibody

Marca:  Invitrogen MA121472

Detalles adicionales : Peso : 0.01000kg

Código de producto. 11521220

  • 339.00€ / 1 ml


Fecha de envío estimada
del proveedor 06-11-2019
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Descripción

Descripción

Phosphatidylinositol 3-kinase (PIK3) is a signaling protein that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. Signaling is initiated when upstream tyrosine kinase receptors or G protein coupled receptors are bound by their ligands. It binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. During insulin stimulation, it also binds to IRS-1. Mutations in the gene can result in Agammaglobulinemia 7, SHORT syndrome, or Immunodeficiency 36.
Especificaciones

Especificaciones

PI3K p85 alpha
Monoclonal
Unconjugated
PIK3R1
Liquid
PIK3R1
Baculovirus expressed (recombit) Bovine p85 alpha subunit of PI 3 Kinase.
1 mL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18708, 25513, 5295
Immunoprecipitation, Western Blot
U13
tissue culture supernatant diluted in 0.2M tris HCl with 5-10% FBS and 0.09% sodium azide; pH 7.4
P27986, P26450, Q63787
GRB1, p85, p85-ALPHA
Mouse
IgG1
RUO
Antibody
Monoclonal
Human, Mouse, Non-human primate, Rat
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