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iNOS Mouse anti-Mouse, Unlabeled, Clone: 54, BD
Mouse Monoclonal Antibody
343.00€ - 565.00€
Especificaciones
| Antígeno | iNOS |
|---|---|
| Clon | 54 |
| Concentración | 250μg/mL |
| Aplicaciones | Western Blot |
| Clasificación | Monoclonal |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
15815459
|
BD Biosciences
610431 |
50 μg |
343.00€
1 set |
Fecha estimada de envío: 24-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
15825459
|
BD Biosciences
610432 |
150 μg |
565.00€
1 set |
Fecha estimada de envío: 24-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
Nitric oxide synthase (NOS), a cell-type specific enzyme, catalyzes the synthesis of nitric oxide (NO). NO is a short-lived radical that transmits cellular signals involved in vasorelaxation, neurotransmission, and cytotoxicity. In macrophages and other cell types, NOS (iNOS or macNOS) activity increases following exposure to cytokines (IFN-γ, TNF-α, and IL-1) and microbial products (lipopolysaccharide (LPS)). iNOS is activated independently of Ca2+/calmodulin and its level of expression is tightly controlled by several transcription factors, including NFκB. Data indicates that TGF-β affects translation of iNOS mRNA and decreases iNOS protein stability. Normally undetectable in brain tissue, iNOS mRNA has been observed in CNS tissues of animals under experimental pathologic conditions. iNOS and nNOS share 51% amino acid homology with the greatest degree of divergence in the calmodulin binding domain. This antibody has been reported to cross-react with nNOS and eNOS.
Immunofluorescence, Immunoprecipitation, Western Blotting
Especificaciones
| iNOS | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG2a κ | |
| Affinity Purified | |
| NOS Type II |
| 54 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Mouse | |
| IgG2a, κ | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.