missing translation for 'onlineSavingsMsg'
Learn More

ERK2 Mouse, Unlabeled, Clone: 33, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 610104

Detalles adicionales : Peso : 0.01000kg

 Ver más versiones de este producto

Código de producto. 15885259

  • 605.34€ / 1 set
Fecha estimada de envío: 17-02-2023
para ver el stock

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.


Descripción

Descripción

The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) are activated after cell stimulation by a wide variety of hormones and growth factors. Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation. Structural analysis of ERK2 indicates that phosphorylation induces a conformational change that exposes the active site for substrate binding. Myriad proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation. Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers. ERK2 is the 42kDa member of the ERK family and is highly homologous to ERK1.

Host Species: Mouse
Clone: 33
Isotype: IgG2b
Species Reactivity: Rat
Immunogen: Rat ERK2 aa. 219-358
Formula Weight [Chemical]: 42kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Especificaciones

Especificaciones

ERK2
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Rat ERK2 aa. 219-358
150 μg
Cell Biology
Rat, Mouse, Human, Frog, Chicken, Canine
IgG2b
Western Blot
33
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Videos
SDS
Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales

For Research Use Only.