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CD95 Mouse, Unlabeled, Clone: 13, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 610198

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15835329

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Descripción

Descripción

CD95 is a member of a family of cell surface receptors that includes tumor necrosis factor receptor (TNF-R), nerve growth factor receptor (NGF-R), CD40, CD27, CD30, and 4-1BB. Both murine and human Fas genes have been cloned and reportedly share 60% similarity in their amino acid sequences. CD95 (Fas) is a cell surface apoptosis-signaling molecule that is widely expressed in sites such as thymus, liver, heart, and ovary. Abnormalities in the Fas gene correlate with autoimmune features in mice and with unusually high levels of lymphocyte apoptosis in HIV-infected humans. Genetic studies have localized the Fas gene near the lpr (lymphoproliferation disease) locus on mouse chromosome 19 and further characterization reportedly has revealed that lpr is a mutation affecting the function of the Fas gene.

Especificaciones

Especificaciones

CD95
Monoclonal
250μg/mL
Fas, APO-1
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot
13
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
150 μg
Cell Biology
Canine, Chicken, Human, Mouse, Rat
IgG2a κ
Sugerencias de productos

Sugerencias de productos

Videos
SDS
Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales

For Research Use Only.