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CD48 Hamster anti-Mouse, PE, Clone: HM48-1, BD

Hamster Monoclonal Antibody

Marca:  BD Biosciences 562398

Detalles adicionales : Peso : 0.00830kg

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Código de producto. 15891879

  • 232.56€ / cada uno
Fecha estimada de envío: 17-02-2023
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Descripción

Descripción

The HM48-1 monoclonal antibody specifically binds to CD48 (previously known as BCM1 in mice, Blast-1 in human, and OX-45 in the rat), a GPI-anchored member of the Ig superfamily. It is widely distributed on leukocytes, but not on non-hematopoietic cells, and its ligands include CD2 (LFA-2) and CD244 (2B4 antigen). The HM48-1 mAb blocks binding of soluble CD2 to CD48-bearing cells, blocks the interaction of CD2 and CD244, inhibits spleen cell proliferative responses to mitogens, augments the proliferative response of spleen cells when cross-linked with anti-CD3e mAbs, and inhibits priming of CTL in vitro. In vivo administration of HM48-1 antibody can prolong survival of cardiac allografts, an effect which is greatly enhanced by the addition of anti-CD2 mAb 12-15. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leukocytes.

Especificaciones

Especificaciones

CD48
Monoclonal
0.2mg/mL
BLAST; BLAST-1; BCM1; HM48-1; MEM-102; Sgp-60; SLAMF2
Hamster
Affinity Purified
RUO
Mouse
IgG1 λ
Flow Cytometry
HM48-1
PE
Aqueous buffered solution containing ≤0.09% sodium azide.
Mouse T lymphoma MBL-2
50 μg
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Videos
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Documentos

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Certificados
Ofertas especiales

Ofertas especiales

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