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CD23 Mouse anti-Human, PE, Clone: M-L233, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 561774

Detalles adicionales : Peso : 0.00860kg

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Código de producto. 15891319

  • 244.00€ / cada uno
Fecha estimada de envío: 23-04-2024
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Descripción

Descripción

The M-L233 antibody specifically binds to human CD23, the low affinity receptor for human IgE (FcεRII). CD23 is a type II membrane glycoprotein that can be expressed by B cells, monocytes, macrophages, eosinophils, platelets and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23-positive cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 25-37 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Especificaciones

Especificaciones

CD23
Monoclonal
PE
Mouse
25 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
M-L233
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Affinity Purified
RUO
Human
IgG1 κ
Sugerencias de productos

Sugerencias de productos

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Documentos

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Ofertas especiales

Ofertas especiales

For Research Use Only.