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CD161a Mouse anti-Rat, FITC, Clone: 10/78, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 555008

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15887948

  • 606.48€ / cada uno
Fecha estimada de envío: 17-02-2023
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Descripción

Descripción

The 10/78 antibody reacts with NKR-P1A, a 60-kDa homodimer expressed on all natural killer (NK) cells and a small subset of T lymphocytes. The 10/78 antibody competes with the previously described 3.2.3 antibody for binding to the antigen. NKR-P1A is a type-II integral membrane protein with an extracellular C-type lectin domain, which is an NK cell-activating receptor specific for tumor target cells. Many rat dendritic cells have been shown to express NKR-P1A, and a subpopulation of these cells has cytotoxic activity. NKR-P1A has also been detected at low levels on peripheral blood monocytes, and its expression is upregulated in IFN-γ-activated monocytes, specifically in a subpopulation of large monocytes with phagocytic capacity. Furthermore, activated peripheral blood neutrophils may express a low level of NKR-P1A. In the mouse and rat, three members of the NKR-P1 gene family have been identified; but in the human gene family, a single NKR-P1 homologue has been discovered and designated Cd161

Especificaciones

Especificaciones

CD161a
Monoclonal
0.5mg/mL
NKR-P1A
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
Oct-78
FITC
Aqueous buffered solution containing ≤0.09% sodium azide.
Not reported
0.5 mg
Immunology
Rat
IgG1 κ
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