CD16 Mouse anti-Human, Brilliant Violet 421, Clone: 3G8, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 562878
Detalles adicionales : Peso : 0.01000kg
The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.
Host Species: Mouse
Isotype: IgG1, κ
Species Reactivity: Hu
Immunogen: Human polymorphonuclear leukocytes
|Brilliant Violet 421|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Human polymorphonuclear leukocytes|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3|
|Rhesus Monkey, Human, Cynomolgus, Baboon|
For Research Use Only.