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TOX3 Antibody (TOX3/1123), Alexa Fluor™ 532, Novus Biologicals™
Mouse Monoclonal Antibody
Marca: Novus Biologicals NBP2-47748AF532
Código de producto. 18176677
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635.00€
600.60€ / 0.10 ml
Ahorro 34.40€
5% Descuento
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Descripción
TOX3 Monoclonal specifically detects TOX3 in Human, Chicken samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.
Especificaciones
| TOX3 | |
| Monoclonal | |
| Alexa Fluor 532 | |
| 50mM Sodium Borate with 0.05% Sodium Azide | |
| TOX3 | |
| Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary) (Uniprot: O15405) | |
| 0.1 mL | |
| Primary | |
| Human, Chicken | |
| IgG2b κ |
| Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence | |
| TOX3/1123 | |
| Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence | |
| CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein | |
| Mouse | |
| Protein A or G purified | |
| RUO | |
| It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts. | |
| Store at 4°C in the dark. |
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