missing translation for 'onlineSavingsMsg'
Learn More

Thrombospondin (TSP) Ab-3, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

Provide accurate, reproducible results with the Epredia™ Thrombospondin (TSP) Ab-3, Mouse Monoclonal Antibody.

Marca:  Epredia MS-420-P1

Detalles adicionales : Peso : 0.00190kg

 Ver más versiones de este producto

Código de producto. 12681387

  • 319.00€ / 500 microlitros

Fecha estimada de envío
21-06-2021

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.


Descripción

Descripción

Thrombospondin is a protein from platelet a-granules. It is made up of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.

Host Species: Mouse

Clone: C6.7

Isotype: IgG1

Species Reactivity: Human, Cow, Pig, Horse, Dog, Sheep and Rat. Others not known.

Epitope: Platelet- or cell-binding domain at the extreme C-terminus of TSP

Immunogen: Ca2+-replete, native purified human TSP from supernatant of thrombin-activated platelets

Molecular Weight: ∽450kDa (Nonreduced)

Cellular Localization: Secretory granules, Golgi complex, endoplasmic reticulum, extracellular matrix Ab-3 shows no cross-reaction with fibronectin, fibrinogen, and von Willebrand factor. It blocks TSP-mediated agglutination of fixed RBCs. It shows no effect on TSP-mediated agglutination of fixed, activated platelets. It inhibits both thrombin- and A23187-induced aggregation of washed, live (not fixed) platelets without affecting the secretion of serotonin. It inhibits adhesion of melanoma G361 cells to TSP. It blocks binding of C-terminal domain to Integrin-Associated Protein (IAP)/CD47.

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting (Nonreduced only)
  • Immunofluorescence
  • Immunoprecipitation (Native verified)
  • Electron Microscopy
  • Flow Cytometry
  • Blocks Binding of TSP-1 to IAP/CD47

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

Thrombospondin (TSP) Ab-3
Monoclonal
200μg/mL
Concentrated
Ca2plus-replete, native purified human TSP from supernatant of thrombin-activated platelets
500μL
Angiogenesis
Primary
Bovine, Canine, Equine, Human, Porcine, Rat, Sheep
Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
C6.7
Unconjugated
Murine
IgG1
RUO
Primary
Monoclonal
Videos
SDS
Documentos