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Invitrogen™ Human SNF1LK2, GST Tag Recombinant Protein

Código de producto. 10064044
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Cantidad:
100 μg
10 μg
Tamaño de la unidad:
100 microgramos
cada uno
Código de producto. Cantidad unitSize
10064044 10 μg cada uno
15428673 100 μg 100 microgramos
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Código de producto. 10064044

Marca: Invitrogen™ PV4792

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Descripción

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

SNF1LK2 (QIK) is a serine/threonine kinase and is a salt-inducible kinase that belongs to the AMP-activated protein kinase family. SNF1LK2 negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1'alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso Q9H0K1
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50mM tris with 2mM DTT, 0.04% Triton X-100, 150mM NaCl, 0.5mM EDTA, 50% glycerol and no preservative; pH 7.5
ID de gen (Entrez) 23235
Peso molecular 131.4 kDa
Nombre Human SNF1LK2, GST Tag
Intervalo de pH 7.5
Método de purificación Purified
Cantidad 10 μg
Requisitos de almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Estado normativo RUO
Alias de gen G630080D20Rik; KIAA0781; LOH11CR1I; QIK; Qin-induced kinase; RGD1559698; salt induceable kinase 2; salt inducible kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; SIK-2; SNF1-like kinase 2; SNF1LK2
Nombre común SIK2
Símbolo de gen SIK2
Familia Quinasa CAMKL Kinase Family
Tipo de producto Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína GST-tag
Secuencia Full length
Contenido y almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Entrada del ensayo Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Grupo de cinasas Ser⁄Thr Kinases: CAMK Group
Condiciones de envío Dry Ice
Compatibilidad de sistemas Z'-LYTE™
Entrada diana SNF1LK2
Gen diana SNF1-like kinase 2
Sistema de expresión Insect cells
Familia de proteínas Kinases & Inhibitors
Forma de proteína Recombinant, Full Length
Formulario Liquid
Subtipo de proteína Serine/Threonine Kinases
Categoría de investigación Signal Transduction
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