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SMAD4/DPC4 Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results with the Epredia™ SMAD4/DPC4 Ab-1, Mouse Monoclonal Antibody.
Marca: Epredia MS-865-PABX
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Descripción
DPC4 (also named SMAD4; small mothers against decapentaplegic deleted in pancreatic carcinoma). The family of SMAD molecules comprises essential mediators of transforming growth factor β (TGF-β) signaling. To date, seven members of this family have been identified, each of which plays a specific and separate role in mediating TGF-β superfamily gene transcription. At least two different members, Smad2 and Smad4/DPC4, have been implicated in human cancer and appear to have tumor-suppressor functions whose inactivation may play an important role in the histogenesis of pancreatic and colorectal malignancy and possibly other human cancers as well.Host Species: Mouse
Clone: SMD46; same as DCS-46
Isotype: IgG1
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Purified recombinant DPC4 protein
Molecular Weight: 60kDa
Positive Control: Ls174T, HT29, Raji, Jurkat cells
Cellular Localization: Nuclear
Recommended for:
Western Blotting
Immunofluorescence
Immunoprecipitation (Native and denatured)
Note:
USA: RUO; Int'l: RUO
Especificaciones
| SMAD4/DPC4 Ab-1 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 200 μL | |
| Cancer and Tumor Biology | |
| Human | |
| IgG1 |
| Immunofluorescence, Immunoprecipitation, Western Blot | |
| SMD46; same as DCS-46 | |
| Unconjugated | |
| Purified recombinant DPC4 protein | |
| RUO | |
| Primary | |
| Concentrated |
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