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IgG1-Fc Recombinant Human Protein, Invitrogen™ Sino Biological™

Código de producto. 13435946
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Cantidad:
5 x 50 μg
5 x 5 μg
50 μg
Unit Size:
25 microgramos
250 microgramos
50 microgramos
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Product Code. Cantidad unitSize
13435946 5 x 50 μg 250 microgramos
13425946 5 x 5 μg 25 microgramos
13455946 50 μg 50 microgramos
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Product Code. 13435946 Supplier Invitrogen Supplier No. 10702HNAH250

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Description

This recombinant human protein is expressed from a DNA sequence encoding the human IgG1-Fc region (AAC82527.1), containing residues 99 to 330, including a 103 Cys/Ser mutation

Immunoglobulin gamma-1 heavy chain constant region, partial (IgG1-Fc), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.&line-break;Background: Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). Recombinant IgG Fc is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.
  • N-terminal Sequence Analysis: Glu 99
  • Activity: 1. Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H1) in a functional ELISA; 2. Measured by its ability to bind human CD16a-AVI-His (Mfr. No. 10389-H27H) in a functional ELISA; 3.Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H) in a functional ELISA
  • Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween™-80
  • Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. Manufactured by Sino Biological (China).

TRUSTED_SUSTAINABILITY

Specifications

Para utilizar con (aplicación) Protein Expression and Isolation, Enzyme and Protein Activity Assay, Protein Assay Control, Reference Standards and Accessories
Peso molecular 26kDa
Cantidad 5 x 50 μg
Requisitos de almacenamiento Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Forma estructural Truncated/Recombinant
Concentración de endotoxinas <1 EU/μg
Alias de gen Fc region of human immunoglobulin G1
Nombre común Fc region of human immunoglobulin G1
Símbolo de gen IgG1-Fc
Etiqueta de proteína IgG1 Fc Tag
Sistema de expresión Mammalian
Familia de proteínas Growth Factors & Receptors
Formulario Lyophilized
Subtipo de proteína Other Proteins
Grado de pureza o calidad ≥95% by SDS-PAGE
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For Research Use Only. Not for use in diagnostic procedures.

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