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Invitrogen™ Human SGK (SGK1), GST Tag Recombinant Protein
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Cantidad:
1 mg
Tamaño de la unidad:
1 miligramo
Descripción
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Catalytic
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
Especificaciones
Especificaciones
| Número de acceso | O00141 |
| Concentración | See Label |
| Para utilizar con (aplicación) | Kinase Assay |
| Formulación | 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5 |
| ID de gen (Entrez) | 6446 |
| Peso molecular | 69.7 kDa |
| Nombre | Human SGK (SGK1), GST Tag |
| Cantidad | 1 mg |
| Estado normativo | RUO - research use only |
| Alias de gen | serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3 |
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