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R&D Systems™ Recombinant Human IL-23 (CHO Expressed) Protein
Descripción
Measured by its ability to induce IL-17 secretion by mouse splenocytes. Aggarwal, S. et al. (2003) J. Biol. Chem. 278:1910. The ED50 for this effect is 0.100-1.00 ng/mL.
Especificaciones
Especificaciones
| Para utilizar con (aplicación) | Bioactivity |
| Formulación | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| ID de gen (Entrez) | 51561 |
| Peso molecular | MolecularWeight-observed: 59-68 kDa, 46-52 kDa & 28-33 kDa, under reducing conditions., MolecularWeight-theroretical: 55 kDa (IL-23 single chain), 37 kDa (p40) & 19 kDa (p19) |
| Cantidad | 100 μg |
| Fuente | Chinese Hamster Ovary cell line, CHO-derived human IL-23 protein Human IL-23 p40 (Ile23-Ser328) Accession # P29460.1 GSGSSRGGSGSGGSGGGGSKL Human IL-23 p19 (Arg20-Pro189) Accession # AAG37232.1 (C-terminus) |
| Requisitos de almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. |
| Concentración de endotoxinas | <0.10 EU / 1 μg of the protein by the LAL method. |
| Alias de gen | IL23, IL-23, IL-23 p19/IL-12 p40, IL-23 A, IL-23-A, IL-23p19, IL-23p19/IL-12p40, IL23P19P19, interleukin 23 p19 subunit, interleukin 23, alpha subunit p19, interleukin-23 subunit alpha, Interleukin-23 subunit p19, JKA3 induced upon T-cell activation, MGC79388, SGRF, SGRFIL-23 subunit alpha |
| Conjugado | Unconjugated |
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