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R&D Systems™ Recombinant Human BMP-4 Protein
Description
Measured by its ability to induce BMP responsive SEAP reporter activity in HEK293 human embryonic kidney cells. The ED50 for this effect is 0.70-7.00 ng/mL. Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al. (2004) Biochem. Biophys. Res. Commun. 315(2):272. The ED50 for this effect is 3.00-30.0 ng/mL.
Specifications
Specifications
| Formulación | Liofilizado a partir de una solución filtrada de 0,2 μm en acetonitrilo y TFA con BSA como proteína transportadora. |
| ID de gen (Entrez) | 652 |
| Peso molecular | M.W. (Observed): 19-24 kDa, reducing conditions 35-41 kDa, non-reducing conditions |
| Nombre | BMP-4 |
| Cantidad | 10 μg |
| Fuente | Mouse myeloma cell line,NS0-derived human BMP-4 protein Ser293-Arg408 |
| Requisitos de almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. |
| Forma estructural | Disulfide-linked homodimer |
| Alias de gen | BMP2B, BMP-2B, BMP2B1, BMP2BMCOPS6, BMP4, BMP-4, Bone morphogenetic protein 2B, bone morphogenetic protein 4, DVR4, MCOPS6, OFC11, ZYME |
| Conjugado | Unconjugated |
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