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PYGL Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

140.00€ - 399.00€

Especificaciones

Antígeno PYGL
Concentración 0.51 mg/mL
Aplicaciones Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Clasificación Polyclonal
Conjugado Unconjugated
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
16816895
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Proteintech
55429-1-AP-20UL
20 μL
140.00€
20 microlitros
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16806895
Ver documentos Detalles de la promoción
Proteintech
55429-1-AP-150UL
150 μL
399.00€
150 microlitros
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Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

This antibody is specific to PYGL. It has no cross reaction to PYGM and PYGB.

This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.
Especificaciones

Especificaciones

PYGL
Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Unconjugated
Rabbit
Human, Mouse
P06737, Q9ET01
110095, 5836
Peptide
Primary
-20°C
PYGL
0.51 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
GSD6, phosphorylase, glycogen, liver, PYGL
PYGL
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documentos

Documentos

Product Certifications