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PMEL17/SILV Antibody (HMB45), PerCP, Novus Biologicals™

Código de producto. 18108604 Tienda Bio Techne Productos
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Cantidad:
0.1 mL
Tamaño de la unidad:
0.10 ml
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18108604 0.1 mL 0.10 ml
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Código de producto. 18108604 Proveedor Novus Biologicals N.º de proveedor NBP234638PCP

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Mouse Monoclonal Antibody

PMEL17/SILV Monoclonal specifically detects PMEL17/SILV in Human, Canine (Negative), Rat (Negative) samples. It is validated for Flow Cytometry, Flow (Intracellular), Multiplex Immunoassay.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno PMEL17/SILV
Aplicaciones Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clasificación Monoclonal
Clon HMB45
Conjugado PerCP
Dilución Flow Cytometry, Flow (Intracellular)
Alias de gen D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Símbolos de los genes PMEL
Especie del huésped Mouse
Inmunógeno Extract of pigmented melanoma metastases from lymph nodes
Peso molecular del antígeno 95 kDa
Método de purificación Protein A or G purified
Cantidad 0.1 mL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 6490
Especificidad de la prueba The gp100 molecule is a 100kDa glycosylated protein that is cleaved into a small (26kDa) carboxy-terminal fragment and a larger amino- terminal section (6038kDa fragments. By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This monoclonal antibody reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This monoclonal antibody stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This monoclonal antibody also stains Angiomyolipoma (PEComa).
Especies diana Human, Canine (Negative), Rat (Negative)
Contenido y almacenamiento Store at 4C in the dark.
Formulario Purified
Isotype IgG1 κ
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For Research Use Only

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