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Invitrogen™ Human PLK1, His Tag Recombinant Protein
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Cantidad:
1 mg
Tamaño de la unidad:
1 miligramo
Descripción
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length
PLK1 is a serine/threonine kinase that is thought to function in cell mitosis and regarded as a marker of cell proliferation. It has been found to play a critical role in carcinogenesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1. Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.
Especificaciones
Especificaciones
| Número de acceso | P53350 |
| Concentración | See Label |
| Para utilizar con (aplicación) | Kinase Assay |
| Formulación | 20 mM HEPES with 0.05% Triton X-100, 0.5 mM EDTA, 0.5 mM EGTA, 150 mM NaCl, 50% glycerol, 5 mM DTT and no preservative; pH 7.5 |
| ID de gen (Entrez) | 5347 |
| Peso molecular | 73.3 kDa |
| Nombre | Human PLK1, His Tag |
| Cantidad | 1 mg |
| Estado normativo | For research use only. Not for use in diagnostic procedures |
| Alias de gen | cell cycle regulated protein kinase; Plk; PLK 1; Plk1; PLK-1; plk1.S; pl x 1; polo (Drosophia)-like kinase; polo like kinase; polo like kinase 1; polo like kinase 1 S homeolog; polo-like kinase; polo-like kinase 1; polo-like kinase homolog; polo-like protein kinase; serine/threonine-protein kinase 13; Serine/threonine-protein kinase PLK1; STPK13; STPK14; Unknown (protein for MGC:133927); XELAEV_18047692mg |
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