missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Proteínas recombinantes
  4. Eurofins DiscoverX Pim1 Protein, Active

Eurofins DiscoverX Pim1 Protein, Active

Código de producto. 17390364
Encompass_Preferred
Click to view available options
Cantidad:
10 μg
250 μg
Tamaño de la unidad:
10 microgramos
250 microgramos
Este artículo no se puede devolver. Vea la política de devoluciones

Código de producto. 17390364

Marca: Eurofins DiscoverX 14573M

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.

Este artículo no se puede devolver. Vea la política de devoluciones

Descripción

Active, N-terminal GST-tagged recombinant human full length Pim-1, for use in Kinase Assays.

Protein serine/threonine kinase PIM1 (pim-1-oncogene) is a member of a small family of highly homologous kinases, including PIM1, PIM2, and PIM3, and all members are expressed in the thymus. Overexpression of each of these members can promote lymphomagenesis in mice. PIM1 associates with Myb and phosphorylates the Myb DNA binding domain, suggesting that it regulates Myb protein activity by direct phosphorylation. Recently four proto-oncogenes PIM1, cMYC, PAX-5 and RhoH/TTF were found hypermutated in diffuse large B cell lymphoma (DLBCL) with >50% of cases carrying at least two mutated genes.

GenBank M27903

Especificaciones

Formulación mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 0.1 mM EGTA, 150 mM NaCl, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Peso molecular 62 kDa
Cantidad 250 μg
Especie Human
Recombinante Recombinant
Etiqueta de proteína N-terminal GST
Sistema de expresión Recombinant enzyme expressed in E. coli cells
Forma de proteína Full-length
Grado de pureza o calidad ≥73%
Expresión Pim-1, active
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.