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![PDGFRA [D842V] Recombinant Human Protein 10μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
PDGFRA [D842V] Recombinant Human Protein
PDGFRA [D842V] Recombinant Human Protein
Marca: Invitrogen PV4203
Detalles adicionales : Peso : 0.05250kg
Descripción
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA D842V is expressed in a high percentage of epithelial ovarian cancers and is implicated in the pathogenesis of acute myelogenous leukemia.Especificaciones
| NP_006197, D842V | |
| Pharma and Biopharma, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 89.7kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| PDGFRA D842V, PDGFR alpha | |
| PDGFRA D842V was pre-diluted in enzyme dilution buffer and assayed in 25mM Hepes (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| Amino acids 550-1089; D842V | |
| 202nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2μg/mL | |
| GST Tag | |
| Kinase and inhibitors | |
| 80% by SDS-PAGE |
| 0.36mg/mL | |
| 114294, 5156 | |
| PDGFRA [D842V] Recombinant Human Protein | |
| –80°C | |
| 1 Each | |
| PDGFRA [D842V] Recombinant Human Protein | |
| PDGFR | |
| PDGFRA [D842V] Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| Receptor tyrosine kinases |
For Research Use Only. Not for use in diagnostic procedures.