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p53 Antibody (TRP/816), Biotin, Novus Biologicals™

Código de producto. 18237981 Tienda Bio Techne Productos
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
18237981 100 μL 100 microlitros
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Código de producto. 18237981

Marca: Novus Biologicals NBP259628B

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Descripción

Mouse Monoclonal Antibody

p53 Monoclonal specifically detects p53 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno p53
Aplicaciones Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoassay, Immunofluorescence
Clasificación Monoclonal
Clon TRP/816
Conjugado Biotin
Dilución Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated
Formulación PBS with 0.05% Sodium Azide
Alias de gen Antigen NY-CO-13, FLJ92943, LFS1TRP53, p53, p53 tumor suppressor, P53cellular tumor antigen p53, Phosphoprotein p53, transformation-related protein 53, tumor protein p53, Tumor suppressor p53
Símbolos de los genes TP53
Especie del huésped Mouse
Inmunógeno Recombinant human full-length p53 protein (Uniprot: P04637)
Método de purificación Protein A or G purified
Cantidad 100 μL
Estado normativo RUO
Disciplina de investigación Apoptosis, Cancer, Cell Cycle and Replication, Cellular Markers, Checkpoint signaling, Core ESC Like Genes, DNA Double Strand Break Repair, DNA Repair, HIF Target Genes, Hypoxia, Neuroscience, Neurotransmission, p53 Pathway, Phospho Specific, Stem Cell Markers, Transcription Factors and Regulators, Tumor Suppressors
Primario o secundario Primary
ID de gen (Entrez) 7157
Especificidad de la prueba The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a 53kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Especies diana Human
Contenido y almacenamiento Store at 4C in the dark.
Formulario Purified
Isotype IgG2a κ
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For Research Use Only (RUO)

Título del producto
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