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NOX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 19013-1-AP-150UL
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Descripción
Mox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase complex expresses in phagocytes, neuroepithelial bodies, vascular smooth muscle cells, and endothelial cells. It includes a membranebound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. The p22- and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. Mox1 and gp91 contain identical C-terminal sequence identity, yet possess distinct expression patterns. gp91-phox expresses in eosinophils, neutrophils, monocytes, and B-lymphocytes, whereas Mox1 is predomitly detected in the colon, with low expression in the uterus and prostate.Especificaciones
| NOX2 | |
| Polyclonal | |
| Unconjugated | |
| CYBB | |
| CYBB, Cytochrome b 245 heavy chain, NOX2, p91 PHOX | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 13058, 1536, 66021 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P04839, Q61093 | |
| Cybb | |
| NOX2 Fusion Protein Ag5536 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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