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Eurofins DiscoverX MSK1 (2-end) Protein, Active
Descripción
MSK1 (mitogen- and stress-activated protein kinases-1, ribosomal protein S6 kinase, 90kDa, polypeptide 5) and MSK2 (mitogen- and stress-activated protein kinases-2, ribosomal protein S6 kinase, 90kDa, polypeptide 4) are activated in vitro by MAPK2/ERK2 or SAPK2/p38. Endogenous MSK is activated by UV radiation, oxidative stress, and other cell-damaging stimuli. MSK may mediate the growth factor and stress-induced activation of CREB.
GenBank AF074393
Especificaciones
Especificaciones
| Formulación | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 50% glycerol, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 1 mM benzamidine, 0.2 mM PMSF, 0.1 % 2-mercaptoethanol. Frozen solution. |
| Peso molecular | 94.4 kDa |
| Cantidad | 10 μg |
| Especie | Human |
| Recombinante | Recombinant |
| Etiqueta de proteína | N-terminal 6His |
| Sistema de expresión | Recombinant enzyme expressed in Sf21 insect cells |
| Forma de proteína | Truncated |
| Grado de pureza o calidad | ≥72% |
| Expresión | MSK1 (2-end), active |
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